What is oxyphilic cells?

Oxyphilic cells, also known as oncocytes, are a type of epithelial cell found in the thyroid gland, parathyroid gland, and some salivary glands. These cells are so-named because they have a large amount of mitochondria, which appears to stain a deep pink color with certain dyes like Hematoxylin and eosin.

Oxyphilic cells have a distinct morphology characterized by an enlarged cytoplasm and prominent mitochondria. They are not typically found in normal tissue but may appear in response to injury or cellular stress. In some cases, oxyphilic cells may be a sign of thyroid cancer or other tumors.

Oxyphilic cells play a role in the synthesis and secretion of hormones, however, their specific function is not completely understood. They are also thought to be involved in the regulation of calcium levels in the blood through the secretion of parathyroid hormone. Overall, oxyphilic cells are important for the proper functioning of the endocrine system but require further research to fully understand their role.